IL-18R Polyclonal Antibody, 100ul[BT-AP04458] Protein Analysis 5-bisphosphate

5-bisphosphate

This protein may also function independently of dynein as a transcriptional modulator

|Contains 1 nuclear receptor DNA-binding domain

thus| it functions as a regulator of a wide variety of downstream proteins| including tumor suppressor proteins p53 and BRCA1| checkpoint kinase CHK2| checkpoint proteins RAD17 and RAD9| and DNA repair protein NBS1

Overexpression of this gene has been associated with acute myelocytic leukemia

IL-18R Polyclonal Antibody, 100ul[BT-AP04458] Protein Analysis 5-bisphosphateInterleukin 18 receptor 1 encoded by IL18R1 is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL 1Rrp2), and IL1RL1